​PEARLS are funded by the New Zealand Ministry of Health and are written by Prof Brian McAvoy, Department of General Practice and Primary Health Care, University of Auckland.

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Title PDF Date #sort ascending
Diuretics have a modest blood pressure lowering effect as second-line therapy for hypertension PDF 02/2010 230
Methyldopa has moderate efficacy in primary hypertension PDF 02/2010 229
Loop diuretics have modest efficacy in hypertension PDF 02/2009 228
Methotrexate effective for maintenance of remission in Crohn's disease PDF 02/2010 227
Pronation may be more effective than supination in correcting pulled elbow PDF 01/2010 226
Rapid viral testing may be beneficial in the emergency department PDF 02/2010 225
No evidence for benefits of homocysteine-lowering interventions for preventing cardiovascular events PDF 01/2010 224
Alpha blockers have modest efficacy in hypertension PDF 07/2011 223
Very limited evidence on effectiveness of assistive technology for rheumatoid arthritis PDF 01/2010 222
Mobile phone-based interventions effective in short term for smoking cessation PDF 01/2010 221
Doxycycline ineffective for osteoarthritis of the knee or hip PDF 12/2009 220
Aldosterone antagonists may prevent progression of chronic kidney disease PDF 11/2009 219
Antimicrobials effective for bacterial vaginosis in non-pregnant women PDF 11/2009 218
Some evidence for efficacy of biologics for rheumatoid arthritis PDF 12/2009 217
Limited evidence for efficacy of antibiotics for Shigella dysentery PDF 12/2009 216
Insufficient evidence of benefit of topical rubefacients for musculoskeletal pain in adults PDF 11/2009 215
Local anaesthetic reduces need for analgesia after caesarean section PDF 11/2009 214
Insufficient evidence for interventions for post-stroke fatigue PDF 11/2009 213
Insufficient evidence for statins in age-related macular degeneration PDF 11/2009 212
Thiazides best first choice for hypertension PDF 10/2009 211
Topical glyceryl trinitrate may be effective in rotator cuff disease PDF 11/2009 210
On-screen computer reminders have a modest effect on care PDF 10/2009 209
Weight-reducing drugs may be beneficial in hypertensive patients PDF 11/2009 208
Psychological interventions may have adverse effects in post-traumatic stress disorder PDF 10/2009 207
Insufficient evidence for garlic in prevention or treatment of the common cold PDF 10/2009 206
Brief interventions may benefit heavy alcohol users admitted to hospital PDF 10/2009 205
Non-pharmacological interventions may comfort children having an anaesthetic PDF 10/2009 204
Chinese herbal medicine may be beneficial in endometriosis PDF 09/2009 203
Pulmonary rehabilitation effective following exacerbations of chronic obstructive pulmonary disease PDF 09/2009 202
Non-steroidal anti-inflammatory drugs of some benefit for the common cold PDF 10/2009 201
Aiming for blood pressure targets lower than 140/90mmHg may not be of benefit PDF 10/2009 200
Social norms interventions reduce alcohol misuse in students PDF 09/2009 199
Antimicrobial prophylaxis effective for colorectal surgery PDF 04/2009 198
Psychological therapies can be of benefit for chronic pain in adults PDF 09/2009 197
Progressive resistance strength training improves physical function in older adults PDF 09/2009 196
Insufficient evidence on repositioning patients for treatment of pressure ulcers PDF 09/2009 195
Written information about medicines improves consumers’ knowledge PDF 09/2009 194
No advantages to using robot-assisted laparoscopic cholecystectomy PDF 08/2009 193
Early amniotomy and early oxytocin reduce caesarean section rate PDF 08/2009 192
Limited benefit to stenting plus angioplasty for superficial femoral artery lesions PDF 08/2009 191
Insufficient evidence for benefit of enteral tube feeding for older people with advanced dementia PDF 08/2009 190
Parenteral parecoxib effective for acute postoperative pain PDF 08/2009 189
Postoperative radiotherapy effective for ductal carcinoma in situ of the breast PDF 08/2009 188
Single dose etoricoxib effective for acute postoperative pain in adults PDF 08/2009 187
Tricyclic antidepressants and selective serotonin reuptake inhibitors effective for depression in primary care PDF 07/2009 186
No evidence of benefit from cannabinoids in dementia PDF 07/2009 185
Limited evidence on effectiveness of maintenance treatments for opiate dependent adolescents PDF 08/2009 184
Upright positions and walking beneficial in first stage of labour PDF 07/2009 183
No evidence on best filling material for the treatment of caries in primary teeth in children PDF 07/2009 182
No evidence for effectiveness of antivirals in preventing postherpetic neuralgia PDF 07/2009 181